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Allopurinol riboside

CAS No. 16220-07-8

Allopurinol riboside ( —— )

产品货号. M26546 CAS No. 16220-07-8

Allopurinol riboside is a metabolite of allopurinol with potency against parasites.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥664 有现货
10MG ¥915 有现货
25MG ¥1466 有现货
50MG ¥2147 有现货
100MG ¥3175 有现货
500MG ¥7557 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Allopurinol riboside
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Allopurinol riboside is a metabolite of allopurinol with potency against parasites.
  • 产品描述
    Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside phosphorylase on inosine with a Ki of 277 μM.(In Vitro):Allopurinol riboside is effective against parasites including leishmaniasis and American trypanosomiasis. Allopurinol riboside is selectively toxic because it is not metabolized by the corresponding enzymes in humans. Humoral immunity is not suppressed by Allopurinol riboside. Lymphocyte blastogenesis induced by PHA and Con A is significantly suppressed by Allopurinol riboside in a concentration-dependent manner.(In Vivo):Low levels of Allopurinol riboside in plasma are attributable to incomplete absorption and rapid renal clearance. Probenecid reduces the renal clearance of allopurinol riboside, extends the half-life of allopurinol riboside in plasma, and triples the levels of allopurinol riboside in plasma. Allopurinol riboside peaks in plasma 1.6 hours after administration, has an elimination half-life of 3 h, and has steady-state concentrations in the therapeutic range.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    16220-07-8
  • 分子量
    268.2
  • 分子式
    C10H12N4O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ncc2c1[nH]cnc2=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Novel nutrients to enhance load-induced muscle hypertrophy. WO2021072450A2
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